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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a42c3ac3e193f31a8d256b84121c92a9b481fb60ec597edec628aab6b8371b5c' 
  AND token = 'jzBHDbvZTNaVzod/reS38r/8UHoo5bjHMID3x3FHjzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}