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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2ef11ba368f8641e3f2295512ec61867456bc2af2ec9fd2360559d9677888093' 
  AND token = 'ZYSfYcdaEFWPzoS/FBBPZL6TJEL2dhgZ017eDXRue6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}