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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3376480dcb253f158a38c3c5e06638f4be402f105c9c4c369bf70b807ccc6f8d' 
  AND token = 'HG7R48m66K6boLyfDOeqrQ55bnpwv8qWzfpQPPnnOFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}