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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5200d4e0e5761a3b681d0a366c4ece67581b378a410559cf82ec9b977ff21e0e' 
  AND token = '2XbVyiv83Wr0l4s955ie8s0/fMDQtWdxn7Bd1WjIf7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}