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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1842d2f7692ff9b56737b60cb729a4bcff0f878a2c00e0b57a1a711405973023' 
  AND token = 'dS6wjeSMPm4UMlswtdqBxrqFEqVfnV42Id0IBRw+Mao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}