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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '86df1b6dd01489fde015819365231c14f2c6def8e5dcfc01372d313b0c52fe22' 
  AND token = 'jQJsixIgFATyTaDj4rZ8TL6/pNv1CEG7u9JQjZys7kM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}