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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4d25effdc4fc67c48d690b275f389f739cbf071e91d8c0e9d386c22632456349' 
  AND token = '5u+E76JRc0UkJNG6qdwtPyT7yJjPrUsofCdT03ECLNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}