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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '24221609e848b1505ed666803b4921b87c27de63345d4edfc2ecb873e08e1bbc' 
  AND token = '16UELdbhZE0g78KUm4m/EbH8maPrKMigLGO0z+3pbIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}