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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2b84100bf1a0aa64bd6fb7af1ec1f879918141150184ef06545b37c69f6e00e8' 
  AND token = 'vNTFxcSxLluo/vtDT4PqbTdBEoQqFaxl6gI9WtTuXKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}