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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65e460db68bca131877618a69eb8f9599cef5f5c3c228e90e44dc1a2ddac1484' 
  AND token = '7VxPxwpEiKVhChyK3aEO9NPxSbyikUNCLFVaSSuax+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}