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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a9a73cf26906e169203d683e7a9e571a2323e4b7e50ade0287c055284b94fa72' 
  AND token = 'Is//7qhKs9QAWbuZdDxmCl2HYwmaE9Nodhh1SpxcdC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}