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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '36f9d754da4385a7bbb63bed196ef781e37da054647ca9cb69841c731249d1ba' 
  AND token = '+JhapMvtM3B2/402C22VkAQg6iWW7L5MYlt2LbLIfm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}