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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b2f0c38b740791e21df1277d0151c872a3b100bc1af5559b7bc2b13799565f0f' 
  AND token = 'GakG5kxArXBKBIdYxMylYzdUDJiXm0t+vZT5cAZY5LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}