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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '161f0a37b6d22166eba5355687728b11d12ba4a92e0404c964e4614e17f2922f' 
  AND token = 'iA4QKj3pyen9itRH9xtbogN/BWaQRcHuVGRyCRcZVCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}