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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5743879db884c25a14f4084c51e57b1512f1dbc14bb87aa4457d46c25c9d3b01' 
  AND token = 'IFiGQ4gYgBHcuxRmnm1yUmE++myPBAsGoK20pdhGpIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}