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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c246dab8970bbc73523cf2a764d033dd3c20b9392da092143e90c2fd6c48bdc6' 
  AND token = 'ctFSfyKA1j1vtdIPY8+wR57TIe8AF5kUnMJOWpBJ/gA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}