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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '459601fee90b4db3c50cef5a874d2069771fea44dafddbada398144b9e364f16' 
  AND token = 'cc4uM3cAp81HuDdvHZZIm3WjpBpQt0vdbFQ1LLhlGGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}