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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1a180b7ea0a2bd91010466536148e5d77c074ea0224502b44c5ece21ba7208a2' 
  AND token = 'bPmPp2Xl72d+OfZ7WKznaZlzM+eAZtVhoYU0+SJcAIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}