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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '243a7c9dacbcb0cba1aa6f579083ba7d866cf943f2daa66877cba69c82d21808' 
  AND token = 'Xa7KlqKmIA7DNRPiMEYJ+rnT26625qHj4UYn1/kr1Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}