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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '37ed36a8f118df27ac10cf231a09b9c14d266ffdb0aac251b50c877f56b29af5' 
  AND token = 'kcS39lfxUJR6VGKGSheVucBt4nuQ3pdAZ5WYJeI2PDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}