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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c77eae44a55e2e1416a761bc283d1aa0639f712a165c9444156e30afd5d2ed6c' 
  AND token = 'Xd+KY0wuKi1vuzRN0KEX42SHYIjOzVJfxXxa2cykwyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}