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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'af6052f1823d2db15cc1932e421b448ba0dad9fcea0dcc0ea5017391f514171d' 
  AND token = 'zyyjv/aa/Q8GtIxb1MAl59abuS8W3Icb8D0Qr691XXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}