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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ac0b086b037f050982a2e723114b4bf297cf24a0e2d49163cc99e3892e2feb0b' 
  AND token = 'kd3E+COx2sqk+xbtrhIEzz6/DILSE4v9cGiG14x60HY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}