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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '845060ba2b6ef47c42a6bab5038b985ca32677771ff6828637fc82b05c5e947d' 
  AND token = 'D4+nEnxhiPOIG2WTz2FZH06HtkOXXNYkvfIIoGDpfy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}