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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49111b5f12790e89e0d55a62ac1063d7c410198277afbb6d925fe7ded468deb3' 
  AND token = 'IeRKd2yYhtoEhKe++X0ImCE5e01D0X4A/go2TVH0N44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}