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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ad7ef73d1eb0775728fac66a33880ced21f6125dbbe48856ee3294d7a52d33d2' 
  AND token = 'VbCm4kN9h280S6o/4lo/1xrTD0nJUV0E44M0hIExORk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}