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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e536019e9f8cd6440a948d77b71cb87c53aa342ca3f535fe9aaa4239a7e69db4' 
  AND token = 'DjNW51PWONHy/g1zOzc4KEAEypngPceUYboNVGtg+OU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}