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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9fcc48c54febc8a4cde7352cf653720e8275defaa777ae245819b03e7f300a9f' 
  AND token = 'dIBp+xnV5NY36N32D+5kh9CiT8F9doeEkY/Vzvf1CI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}