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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0cf80f50565bff7e205e0ca0e0d262043f661f6bab934c80b5a3b357fd20203a' 
  AND token = 'x06OKAlykNYyTfdkp3L+RDm/WmAGVs692+8o5WpITlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}