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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65ff54010add710a4689ad896ad33b8451be2a6359160c94d550dee935f9625f' 
  AND token = 'peKd9DKCS5pfc85P+5pymXaTrGdIigN6FLP63uOXupc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}