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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '42a930e787d3e46f07fc25de3ae164c96b61abb1ad988e865d9281014f26000f' 
  AND token = 'sZsFeoywaE08oEGW/HaKgLbWfitShw9adOwFIyMy8gI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}