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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '48dffa48a4836c2d5b81fbf6ad26c0a010e20f4b578b92f079e54cddb4b41e05' 
  AND token = 'MFw3vfgNbDtpxAKq0bphtAG+IUfHuKApkdeT7QAfGNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}