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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21b6ac52a2a25c852707e5e0b7ab10418c98b2fd041be96feee51fcd1ff1d06b' 
  AND token = '3TUkaSA3xoNqhHNZ3G6aTynq7Z+90ayUhKxhQag19uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}