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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5e4f3d06dfa3b9aebdf257855f5e3c540b3c9c66f7207e3fe47e98ba765ef806' 
  AND token = 'lZWBls8G/dR/jqPag9u9X00Kh7Wyb7K9fdEIcEMoGAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}