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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '091412cc329134d13c04b2ade674c5bab95725ff329a7925f7dcacbf3a71a8b1' 
  AND token = 'aeMfU2a5uasz9yCuzAhyJQZc4j/TY7MbXSwwGulbKjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}