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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8b9bdbaf400e1b63a806e4abdc41e38494f0c5005fada029d1505966fb708034' 
  AND token = '0t24Y0PaZu9ZJ1QbSaTOuSosqIKMU4N8BH8YXh++Ejs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}