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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21be360615eeea551fae6ff47bc9cd7684008b87f403ed8098727f3eb5573667' 
  AND token = 'C+a/JdbmfShFeh3o3x14hbmpuuwXU/c4luaDEI6XQOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}