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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22de684d8093f6b2252cef6f3fae593609cedff9ec0f8f80e12c3aefcd60c8a5' 
  AND token = 'A+WJYbe2a4Pz3EIV0/QWE506LK1NEkRk0LS6j7Bviy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}