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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3cfc7e6acc173e789bbdc8a89d76880f0e2ebc31d4d700de9271099224426c35' 
  AND token = 's9/c3cWj+3JCSxZBxGacJJtLFcQIKPEmyyz2Fc4yn7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}