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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a4c7814c733dbbf46a82f66f1281e17b683ec1ca88c6303888b1c2113dd980df' 
  AND token = 'RlWq0fbm/yrzVc/o5NZ6S/vYqRMo38gLO9K8qCYI5Wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}