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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '25863c24c5d1268d30b7bbaf8383b54f07a4535e4b080df57534d5d22eb0da47' 
  AND token = 'FdGyqTi9OGuyhKakB0v1X+STUxJMwsd5KNM4cV7Niic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}