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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'db5b469abbc2b12e830025a81bcdc17904e673201a5f43e19d800f41f10bb388' 
  AND token = 'dz/ynD+HiPnxnOM28SRVY5lhWho+r+Wmn7EfHsRILZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}