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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0e375581c937dd3be559e41c74698212170a573d9986332f50c8ea439dcafc40' 
  AND token = 'ViwM5VGT30QvLuIDXa+2xMQIIvasq4c/5rfVzDcodpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}