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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21505401c8158e900b93cb7f723837dd93ba991124ebe0e5f6155f908445b3a7' 
  AND token = 'vAGnmUvO1VkFyJgA1lsoUm19xmEwZb9VzwkMRCtg8Cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}