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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f3f2201cc030a59808ffc220ebab44c3a5e371d64a47712e78b55998ee306cf5' 
  AND token = '2AU2TcQGW+ZHf/00rSYtZUmQwxHWKRCSCdaTk/1F2mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}