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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3918ce127fcb741e7b8b174c37e5dc79f8eba96b7bdc365cf90504fca4808e8f' 
  AND token = 'jH4JeHheTdgSZVYsFBUdpaTk5mxaWcG+nqZZj9cPfcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}