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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '202a716f5f912bffc1180f6645c5c56df429d333bd2bc969b5a5b6aa1cc65af3' 
  AND token = 'FYfu/JDy9tBs5o8HPOV1euxnBRcaZBLvkWWS5djoTmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}