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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6a573d9edfabd132b4e6857d646c167029b4a1cd2c5652a97bfd04d9f01841d2' 
  AND token = 'bwbOeVsfH6DNpdV/DeSm16wYgZmib2SdDYL7uEM+0ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}