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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e45d586f9e0c88a7a2b8c31645e4647dbfde5f5290e82d2279589f1f209e5cda' 
  AND token = 'SpSMSssb7TIjFncdWMDYtaInRUXl9an30aDat13atuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}