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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '03483d6a29ad30109aed5d19fde5e0229dd7f922adb2bf566bd4acab45a518c6' 
  AND token = '22A767zxolH5nla77EFkGTA0mhrjALUv6CCbZz1MvCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}